By Malcolm Carruthers
Simply what's the andropause? even supposing attractiveness of the andropause notion by way of the scientific neighborhood is becoming, it truly is nonetheless a hotly debated factor. yet as a hectic clinician you've got sufferers to regard and also you want details. So the place are you able to locate the data you must comprehend, diagnose, and deal with this ? Androgen Deficiency within the grownup Male: explanations, analysis and therapy distills the information received by way of writer Dr. Malcolm Carruthers in his 25 years of study and scientific adventure in diagnosing and treating the andropause right into a complete, particular medical resource.
Dr. Carruthers records the heritage of the quest for testosterone remedy from antiquity to the awarding of the Nobel Prize to Adolf Butenandt and Leopold Ruzicka for synthesizing testosterone and patenting its creation a few 4,000 years later. He discusses the explanations of androgen deficiency, the male menopause or andropause, and up to date advances in its prognosis. The textual content contains experiences of the literature in each one part and a fund of bibliographic references gleaned from the author's years of study during this box. this mixture of positive factors makes Androgen Deficiency within the grownup Male: reasons, prognosis and remedy a useful and useful scientific consultant, a whole and particular reference quantity, and a cohesive and readable textbook.
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Extra info for Androgen deficiency in the adult male : causes, diagnosis, and treatment
In America, however, the reactions to Brown-Séquard’s work were overenthusiastic, and the testicular extract was widely inflicted by charlatans on a gullible public as ‘the elixir of life’ for every type of ailment from senility to tuberculosis. This and other ‘organotherapies’ became even more fashionable because of the simultaneous introduction of ‘serotherapies’, the use of sera and vaccines of animal origin for the prevention and treatment of infectious diseases. Particularly in Victorian Britain, studies in matters relating to sexual activity were considered unsuitable topics for research.
Brown-Séquard’s mistake at the end of a long and innovative career in research is still being used by opponents as evidence against the existence of the andropause to this day. Even learned and very influential physiologists such as Sir Edward Schafer, who wrote many papers and a book on Endocrine Organs, had a Freudian block about reproductive hormones, and in a lecture on ‘Internal Secretions’ given to the British Medical Association in London in 1895, he denied that the testes had any endocrine actions.
This was both effective and convenient, as the implant continued to act for 6 months9. Sixty years later this is still one of the best methods of giving long-term testosterone treatment. There are few medical preparations, particularly in endocrinology, which have stood the test of time so well. A third type of preparation which was also made in the early years was a water-soluble form called methyltestosterone. Unfortunately, although effective in relieving symptoms, this proved very toxic, especially to the liver.
Androgen deficiency in the adult male : causes, diagnosis, and treatment by Malcolm Carruthers